US Open 2025 results: Jannik Sinner beats Alexei Popyrin to reach third round

Elsewhere, Poland’s Kamil Majchrzak produced a superb comeback to knock out Russian ninth seed Karen Khachanov in an epic second-round contest.

Majchrzak came back from two sets down, overturned a 5-2 fifth-set deficit and saved five match points to come through 2-6 6-7 (4-7) 6-4 7-5 7-6 (10-5).

Meanwhile, Russian Andrey Rublev came through a tough four-set encounter with American Tristan Boyer.

Boyer, ranked 113th in the world, extended the match by taking the third set before 15th seed Rublev completed a 6-3 6-3 5-7 7-6 (7-4) victory .

Rublev’s next opponent will be Coleman Wong, who backed up his history-making first-round victory against Aleksandar Kovacevic with a four-set win over Australia’s Adam Walton.

Wong’s first-round success made him the first male player from Hong Kong to win a Grand Slam singles match in the Open era.

Lorenzo Musetti was a 6-4 6-0 6-2 winner over Belgian veteran David Goffin and the 10th seed will face fellow Italian Flavio Cobolli next.

Cobolli, the 24th seed, won a match tie-break to beat American Jenson Brooksby in a marathon second-round match that lasted more than four and a half hours.