Diamondbacks at Brewers Prediction: Odds, expert picks, starting pitchers, trends, stats for August 26

It’s Tuesday, August 26 and the Diamondbacks (64-67) are in Milwaukee to take on the Brewers (81-50). Brandon Pfaadt is slated to take the mound for Arizona against Jacob Misiorowski for Milwaukee.

The Brewers beat the Diamondbacks, 7-5, on Monday to get back in the winning column. The Brewers had previously lost two consecutive games but improved to 3-5 over the last eight games with the victory. Arizona has fallen to 4-2 over the past six games as they attempt to win three consecutive series.

Let’s dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Diamondbacks at Brewers

• Date: Tuesday, August 26, 2025
• Time: 7:40PM EST
• Site: American Family Field
• City: Milwaukee, WI
• Network/Streaming: ARID, FDSNWI

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Diamondbacks at the Brewers

The latest odds as of Tuesday:

• Moneyline: Diamondbacks (+132), Brewers (-158)
• Spread: Brewers -1.5
• Total: 8.0 runs

Probable starting pitchers for Diamondbacks at Brewers

• Pitching matchup for August 26, 2025: Brandon Pfaadt vs. Jacob Misiorowski
  • Diamondbacks: Brandon Pfaadt, (12-8, 4.95 ERA)
    Last outing: 2.57 ERA, 2 Earned Runs Allowed, 5 Hits Allowed, 0 Walks, and 5 Strikeouts
  • Brewers: Jacob Misiorowski, (4-2, 4.19 ERA)
    Last outing: 6.75 ERA, 3 Earned Runs Allowed, 1 Hits Allowed, 3 Walks, and 5 Strikeouts

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Diamondbacks at Brewers

• Milwaukee is 2-2 versus Arizona this season
• Milwaukee is 4-6 in the last 10 games
• The Brewers have won 15 of their last 20 home games
• Arizona is 4-2 in the last 6 games
• The Diamondbacks have failed to cover the Run Line in 3 straight road games

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Diamondbacks and the Brewers

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Tuesday’s game between the Diamondbacks and the Brewers:

• Moneyline: NBC Sports Bet is recommending a play on the Milwaukee Brewers on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Arizona Diamondbacks at +1.5.
• Total: NBC Sports Bet is staying away from a play on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.

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• Jay Croucher (@croucherJD)
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• Vaughn Dalzell (@VmoneySports)
• Trysta Krick (@Trysta_Krick)